行业专家 -米乐体育官方

刘军
性      别: 职      称: 副教授
籍      贯: 黑龙江 现 居 地: 黑龙江
毕业院校: 西北农林科技大学 专      业: 临床兽医学
出生年月: 1981-10-11 工作单位: 西北农林科技大学动物医学院
邮       箱: liuluo1028@163.com 联系电话: 87080092
学       历: 博士

【人物简介】

刘军,男,1981年10月出生,黑龙江人,博士,副教授,硕士生导师。   教育及研究经历   教育经历:   2000年6月毕业于西北农林科技大学动物科技学院动物医学专业,获学士学位。   2007年6月毕业于西北农林科技大学动物医学院临床兽医学专业,获硕士位。   2011年6月毕业于西北农林科技大学动物医学院临床兽医学专业,获博士位。   研究经历:   2011年7月到2013年6月在西北农林科技大学生命科学院发育生物学博士后流动站工作。   2013年6月至今,在西北农林科技大学动物医学院农业部动物生物技术重点实验室从事动物胚胎工程、动物抗病育种等研究。   2013年6月到2013年12月任职讲师,2014年1月至今任副教授。

【研究方向】

目前主要开展山羊胚胎早期发育、动物克隆和转基因动物等方向的研究。

【研究成果】

  2015年获陕西省科技进步一等奖“牛羊基因定点精确编辑技术研究与应用”一项,成果完成人排名第五。   2013年获陕西省科技进步一等奖“牛羊良种繁育关键技术研究与应用”一项,成果完成人排名第三。   获批国家科技发明专利两项:(1)201110251106.5,一种牛囊胚内细胞团细胞和滋养层细胞的差异染色方法(2013);(2)zl201210269209.9,一种 hsa 乳腺特异性表达载体及其构建的重组细胞(2014)。

【科研项目】

  1. 陕西省科技统筹创新工程计划项目:利用乳腺生物反应器技术表达猪蓝耳病病毒重要结构蛋白 2015.1-2017.12,20万元,主持人;   2. 国家自然科学基金:tet3 蛋 白 在 山 羊 早 期 胚 胎dna 甲基化重编程过程中的作用 2014.1-2016.12,25万元,主持人;   3. 西北农林科技大学基本科研业务费:细菌诱导型β-防御素3抗乳腺炎奶山羊模型的研制 2014.1-2017.1,10万元,主持人;   4. 西北农林科技大学博士科研启动基金:供体细胞表达卵母细胞因子pgc7对山羊克隆胚胎发育能力的影响 2014.1- 2015.12,5万元,主持人;   5. 中国博士后科学基金:pgc7 对山羊克隆胚胎基因组印记的维持作用 2012.7-2013.6,5万元,主持人。

【论文著作】

  1.cui c#, song y#, liu jun#, ge h, li q, huang h, hu l, zhu h, jin y*, zhang y*: gene targeting by talen-induced homologous recombination in goats directs production of β-lactoglobulin-free, high-human lactoferrin milk. scientific reports 2015, 5.   2.ru k, su f, zheng y, zhang y, luo y, guo z, he x, liu x, zhang y, liu j*: inducible expression of enhanced green fluorescent protein by interleukin-1α, interleukin-1β and toll-like receptor 2 promoters in goat mammary epithelial cells in response to bacterial challenges. the veterinary journal 2015, 203(1):85-91.   3.zhang m, zheng y, chen w, zhang y, guo z, zhang y*, liu j*: identifying an optimal promoter sequence of goat β-lactoglobulin gene for constructing high-expression vectors in mammary epithelial cells. small ruminant research 2015.   4.luo y, wang y, liu j, lan h, shao m, yu y, quan f, zhang y*: production of transgenic cattle highly expressing human serum albumin in milk by phic31 integrase-mediated gene delivery. transgenic research 2015, 24(5):875-883.   5.liu j#, wang y#, su j, wang l, li r, li q, wu y, hua s, quan f, guo z, zhang y*: effect of the time interval between fusion and activation on epigenetic reprogramming and development of bovine somatic cell nuclear transfer embryos. cellular reprogramming 2013, 15(2):134-142.   6.liu j, wang y, su j, luo y, quan f, zhang y*: nuclear donor cell lines considerably influence cloning efficiency and the incidence of large offspring syndrome in bovine somatic cell nuclear transfer. reproduction in domestic animals 2013, 48(4):660-664.   7.yang z#, liu j#, liu h, qiu m, liu q, zheng l, pang m, quan f*, zhang y*: isolation and characterization of ssea3 stem cells derived from goat skin fibroblasts. cellular reprogramming 2013,15(3):195-205.   8.luo y#, liu j#, liu q, zheng l, wang y, su j, hu g, zhang y*: chicken hypersensitive site-4 insulator increases human serum albumin expression in bovine mammary epithelial cells modified with phic31 integrase. biotechnology letters 2013, 35(4):529-537.   9.luo y#, liu j#, wang y, su j, wu y, hu g, gao m, quan f, zhang y*: phic31 integrase‐mediated genomic integration and stable gene expression in the mouse mammary gland after gene electrotransfer. journal of gene medicine 2013, 15(10):356-365.   10.liu j#, luo y#, ge h#, han c, zhang h, wang y, su j, quan f, gao m, zhang y*: anti-bacterial activity of recombinant human β-defensin-3 secreted in the milk of transgenic goats produced by somatic cell nuclear transfer. plosone 2013, e65379.   11.liu j, yang z, qiu m, luo y, pang m, wu y, zhang y*: developmental potential of cloned goat embryos from an ssea3 subpopulation of skin fibroblasts. cellular reprogramming 2013, 15(2):159-165. if: 1.788   12.liu j#, luo y#, zheng l, liu q, yang z, wang y, su j, quan f, zhang y*: establishment and characterization of fetal fibroblast cell lines for generating human lysozyme transgenic goats by somatic cell nuclear transfer. transgenic research 2013, 22(5):893-903.   13.liu j, luo y, liu q, zheng l, yang z, wang y, su j, quan f, zhang y*: production of cloned embryos from caprine mammary epithelial cells expressing recombinant human β-defensin-3. theriogenology 2013, 79(4):660-666.   14.liu j, li l, du s, bai x, zhang h, tang s, zhao m, ma b, quan f, zhao x, zhang y*: effects of interval between fusion and activation, cytochalasin b treatment, and number of transferred embryos, on cloning efficiency in goats. theriogenology 2011, 76(6):1076-1083.   15.liu jun, tang shuang, xu wei, wang yongsheng, yin baoying, zhang yong*, detrimental effects of antibiotics on mouse embryos in chromatin integrity, apoptosis and expression of zygotically activated genes, zygote, 2011, 19(2): 137-145.   16.tang shuang, liu jun, du shan, li liangliang, zhengcongying, zhao mingtao, wang yongsheng, zhang yong*, optimization of embryo culture conditions in the production of cloned goat embryos, following somatic cell nuclear transfer, small ruminant research, 2011, 96(1): 64-69.

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